Mr Siddharth Sinha

Neurosurgery Resident, London Deanery.  I am a neurosurgery resident based in the London Deanery. I graduated with Distinction from the University of Manchester (MBChB, 2020) and hold an MRes from Imperial College London and a BSc in Microbiology from the University of
Leeds. I completed Academic Foundation Training at King’s College Hospital and subsequently undertook a Clinical Research Fellowship at Queen Square under the supervision of Professor Hani Marcus, developing research experience in skull base surgery and intraoperative technologies. I have an extensive publication record in neuro-oncology, skull base, spinal surgery, and surgical data science, with multiple international presentations and national podium talks.

Publications

Sinha S, Williams SC, Hanrahan JG, Muirhead WR, Booker J, Khalil S, Kitchen N, Newall N, Obholzer R, Saeed SR, Marcus HJ, Grover P. Mapping the Clinical Pathway for Patients Undergoing Vestibular Schwannoma Resection. World Neurosurg. 2024 Oct;190:e459-e467. doi: 10.1016/j.wneu.2024.07.157. Epub 2024 Jul 27.

Sinha S, Kalyal N, Gallagher MJ, Richardson D, Kalaitzoglou D, Abougamil A, Silva M, Oviedova A, Patel S, Mirallave-Pescador A, Bleil C, Zebian B, Gullan R, Ashkan K, Vergani F, Bhangoo R, Pedro Lavrador J. Impact of Preoperative Mapping and Intraoperative Neuromonitoring in Minimally Invasive Parafascicular Surgery for Deep-Seated Lesions. World Neurosurg. 2024 Jan;181:e1019-e1037.

Sinha S, Avnon A, Perera A, Lavrador JP, Ashkan K. Butterfly gliomas: a time for stratified management? Neurosurg Rev. 2023 Sep 4;46(1):223.

Sinha S, George KJ. “The fate of nonoperative management in patients with lytic spondylolisthesis”. J Neurol Surg A Cent Eur Neurosurg. 2022 Jan 21.

Sinha S, Toe KKZ, Wood E, George KJ. “The impact of COVID-19 on neurosurgical head trauma referrals and admission at a tertiary neurosurgical centre.” J Clin Neurosci. 2021;87:50-54.

Lee CA, Sinha S, Fitzpatrick E and Dhawan A. “Hepatocyte transplantation and advancements in alternative cell sources for liver-based regenerative medicine.” J Mol Med (Berl). 2018 Jun;96(6): 469-481. (Joint Lead Author).

de los Reyes-Nabhan NK, Sinha, S, Noorani, I. “Comparing Utility of Intraoperative Magnetic Resonance Imaging and 5-Aminolevulinic Acid in High-Grade Glioma Resection Surgery: A Systematic Review and Meta-Analysis.” Neurosurgery Practice. 2025 Sept; 6(3):e000146.

Booker J, Penn J, Fersht N, Hanrahan JG, Kosmin M, Newall N, Sinha S, Williams SC, Thorne L, Hill CS, Marcus HJ. Mapping patient encounters to identify recruitment timepoints after brain tumour surgery: a cohort and cross-sectional study. BMJ Open Qual. 2025 May 14;14(2):e003065. doi: 10.1136/bmjoq-2024-003065.

Williams SC, Duvaux D, Das A, Sinha S, Layard Horsfall H, Funnell JP, Hanrahan JG, Khan DZ, Muirhead W, Kitchen N, Vasconcelos F, Bano S, Stoyanov D, Grover P, Marcus HJ. Automated Operative Phase and Step Recognition in Vestibular Schwannoma Surgery: Development and Preclinical Evaluation of a Deep Learning Neural Network (IDEAL Stage 0). Neurosurgery. 2025 Apr 30. doi: 10.1227/neu.0000000000003466. Epub ahead of print.

Booker J, Penn J, Noor K, Dobson RJB, Fersht N, Funnell JP, Hill CS, Khan DZ, Newall N, Searle T, Sinha S, Thorne L, Williams SC, Kosmin M, Marcus HJ. Utilising Natural Language Processing to Identify Brain Tumor Patients for Clinical Trials: Development and Initial Evaluation. World Neurosurg. 2025 May;197:123907. doi: 10.1016/j.wneu.2025.123907. Epub 2025 Mar 18.

Awan M, Elshalakany A, Kalaitzoglou D, Kalyal N, Sinha S, Perera A, Wroe Wright O, Gallagher MJ, Richardson D, Elhag A, Marchi F, Abougamil A, Silva M, Oviedova A, Patel S, Mirallave-Pescador A, Diaz-Baamonde A, Bleil C, Zebian B, Gullan R, Ashkan K, Vergani F, Bhangoo R, Lavrador JP. Diffusion changes in minimally invasive parafascicular approach for deep-seated tumours: impact on clinical outcomes. Neurosurg Rev. 2025 Jan 18;48(1):63. doi: 10.1007/s10143-024-03160-y.

Williams S, Noor K, Sinha S, Dobson RJB, Funnell JP, Hanrahan JG, Muirhead W,Kitchen N, Kanona H, Khalil S, Saeed S, Marcus HJ and Grover P. Concept Recognition and Characterization of Patients Undergoing Resection of Vestibular Schwannoma Using Natural Language Processing. J Neurol Surg B Skull Base. Published online 2023. doi:10.1055/S-0044-1786738/ID/JR23NOV0176-30/BIB

Booker J, Penn J, Newall N, Rowland D, Sinha S, Marcus HJ. Development and early Evaluation of a novel tool for assessment of individualised risk tolerance during surgical consent. Br J Neurosurg. 2024 Oct 17:1-6. doi: 10.1080/02688697.2024.2413453. Epub ahead of print.

Booker J, Penn J, Noor K, Dobson RJB, Funnell JP, Koh CH, Khan DZ, Newall N, Rowland D, Sinha S, Williams SC, Sayal P, Marcus HJ. Early evaluation of a natural language processing tool to improve access to educational resources for surgical patients. Eur Spine J. 2024 Jul;33(7):2545-2552. doi: 10.1007/s00586-024-08315-5. Epub 2024 May 30.

Booker J, Penn J, Koh CH, Newall N, Rowland D, Sinha S, Hanrahan JG, Williams SC, Sayal P, Marcus HJ. Mapping patient education encounters in elective surgery: a cohort study and cross-sectional survey. BMJ Open Qual. 2024 May 27;13(2):e002810. doi: 10.1136/bmjoq-2024-002810.

Lee C, Dhawan A, Iansante V, Filippi C, Mitry R, Tang J, Walker S, Fernandez DaCosta R, Sinha S, Hughes RD, Koulmanda M and Fitzpatrick E. “Improving engraftment of hepatocyte transplantation using alpha-1 antitrypsin as an immune modulator.” J Mol Med (Berl). 2019 Apr;97(4):563-577.

Starup-Hansen J, Newall N, Dimitrakakis E, Khan DZ, Dwyer G, Iyengar K, Psychogyios D, Hanrahan JG, Sinha S, James Booker J, Stoyanov D, Marcus HJ. A Handheld Robot for Endoscopic Endonasal Skull Base Surgery: Updated Preclinical Validation Study (IDEAL Stage 0). J Neurol Surg B Skull Base. Published online 2023. doi:10.1055/A-2297-3647/ID/JR23OCT0168-27/BIB

Newall N, Khan DZ, Hanrahan JG, Booker J, Borg A, Davids J, Nicolosi F, Sinha S, Dorward N, Marcus HJ. High fidelity simulation of the endoscopic transsphenoidal approach: Validation of the UpSurgeOn TNS Box. Front Surg. 2022 Dec 6;9:1049685. doi: 10.3389/fsurg.2022.1049685.

Gilani S, Pankhania K, Aruketty M, Naeem F, Alkhayyat A, Akhtar U, Chaudhary M, Sinha S. “Twelve tips to organise a mock OSCE.” Med Teach. 2021” Mar 3:1-20

Baig Mirza A, Bartram J, Sinha S, Gebreyohanes A, Boardman T, Vastani A, Dyson E, Lavrador JP, Russo V, Choi D, Vasan AK, Grahovac G. “Surgical management and outcomes in spinal intradural arachnoid cysts: the experience from two tertiary neurosurgical centres.” Acta Neurochir (Wien). 2021 Oct 27. doi: 10.1007/s00701-021-05027-3. Epub ahead of print.

Wilkinson T, Sinha S, Peek N, Geifman N. “Clinical trial data reuse – overcoming complexities in trial design and data sharing.” Trials. 2019 Aug 19;20(1):513.

Book chapter
Sinha S, Booker J, Newall N, Nicolosi F and Marcus HJ, Future of The Future of Neurosurgery, Ethical Challenges for the Future of Neurosurgery. Published online 2024:343-361.

Case Reports

Sinha S, Iyer V, George KJ. “Foramen magnum osteochondroma causing myelopathy in a patient with hereditary multiple exostoses. Surg Neurol Int. 2020 Sep;11:296.

Sinha S, George KJ. “Spinal cord herniation following multilevel anterior cervical discectomy and fusion: A case report and literature review” Surg Neurol Int. 2020 Oct;11:327